Tuesday, October 6. 2015New Prenatal Test Will Screen Whole Fetal GenomeThis is the age of the non-invasive prenatal tests, called NIPTs for short. NIPTs look at minute quantities of fetal DNA floating in a pregnant mother’s blood. With these small pieces of DNA scientists can look for genetic abnormalities in the fetus. The tests are “non-invasive” because they only require a blood sample from mom. Monday, March 23. 2015New Prenatal Screens’ Seek-and-Destroy Mission
In December 2014, the New England Center for Investigative Reporting (NECIR) released its research into the new non-invasive prenatal-screening tests that are now being offered to pregnant women.
These tests look at minute amounts of placental DNA that are in the mother’s blood. This small amount of fetal DNA can be detected as early as 10-weeks’ gestation. The tests only require a blood sample, and they give a couple a non-invasive, early look at the genetic health of their unborn baby. The NECIR exposé, titled “Oversold and Misunderstood,” is shocking. While many of the companies offering these new screens, which are not approved by the Food and Drug Administration, tout that the tests are “99% accurate,” the center uncovered that these tests gave false alarms nearly half the time, especially for rare chromosomal abnormalities like trisomy 13. This means that perfectly healthy fetuses are being aborted because of the results of these screens. The NECIR reports: “And at Stanford University, there have been at least three cases of women aborting healthy fetuses that had received a high-risk screen result.” “The worry is women are terminating without really knowing if [the initial test result] is true or not,” said Athena Cherry, professor of pathology at the Stanford University School of Medicine, whose lab examined the cells of the healthy aborted fetuses. In one of the three Stanford cases, the woman actually obtained a confirmatory test and was told the fetus was fine, but aborted anyway because of her faith in the screening company’s accuracy claims. “She felt it couldn’t be wrong,” Cherry said. The NECIR concludes that “companies are overselling the accuracy of their tests.” It is a tragedy when any child is aborted, for sure, but it seems particularly horrifying that babies are being torn from their mothers’ wombs because of misleading, even predatory, marketing. How has this happened? When did we become a society where the lives of the next generation hinge on the results of a single test that is not even regulated by the FDA? As someone who has performed genetic testing for thousands of patients, I can say that the problem is deep and multifaceted. Continue reading at the National Catholic Register>> Friday, January 9. 2015Coming to America...For Sex Selection
Life, liberty and the pursuit of happiness. It was for these inalienable rights that the American colonists declared their independence. It is also for these rights that millions have traveled to our shores looking for opportunity and a better life.
There is another right, not enumerated in our Constitution, that Americans regrettably hold dear enough that it often trumps all the others. Foreigners are traveling to the U.S. to exercise this right as well. That right is the “reproductive right.” Decades ago, when abortion on demand became the law of our land, reproductive rights meant that a woman could terminate her unborn child for any reason. Today, the meaning of reproductive rights has expanded to include creating children any way one sees fit and tossing out any offspring who do not fulfill one’s desires. Our warped understanding of reproductive rights means that, in most states, sex selection is perfectly legal. If an American wants a child of a certain sex, then many believe that is his or her “reproductive right.” Our lax attitude toward sex selection is not shared around the world. Many countries, like Australia, Canada, France, Germany, South Korea and the United Kingdom, to name just a few, have restrictions on sex selection. Even in China and India, sex selection is illegal, although it still remains a problem in those countries. These societies have acknowledged that choosing who gets to live based simply on gender is an unethical practice they will not sanction. As a result, the United States has become a safe haven for sex selection. Whether through sex-selective abortion or through in vitro fertilization (IVF) with preimplantation genetic diagnosis (PGD), immigrants and foreigners with gender bias are taking advantage of our lack of restrictions. Continue reading at the National Catholic Register>> Monday, December 15. 2014New Prenatal Screens Lead to Abortion of Healthy BabiesAn excellent piece by Beth Daley from the New England Center for Investigative Reporting called "Overused and Misunderstood" is a must read. It is about the new non-invasive prenatal screening tests offered by companies that claim they are 99% accurate. These screens are done early in pregnancy using only a maternal blood sample giving couples an eariler look at the health of their unborn baby. The problem is that these are screening tests but are being used as diagnostic tests. What is the difference? A screen is a test given to a general healthy population and usually has high sensitivity so that any possible problems are flagged. Because of the high sensitivity, false positives are more common. Also, screens are not necessarily approved by the FDA. A screen is always supposed to be confirmed with a diagnostic test. A diagnostic test is designed with high specificity for a particular condition flagged by the screen. It is often more invasive and is meant as a tool to make a definitive diagnosis. Because these new, non-invasive, prenatal screening tests are being touted as "99% accurate" and having "near-diagnostic accuracy," parents are skipping the confirmatory diagnostic tests like CVS and amniocentesis and are going straight for abortion if the screen indicates a genetic problem. Daley reports on the Chapmans that almost aborted their healthy son: Stacie Chapman’s heart skipped when she answered the phone at home and her doctor — rather than a nurse — was on the line. More worrisome was the doctor’s gentle tone as she asked, “Where are you?”The Chapmans are not alone. Daley exposes that: Two recent industry-funded studies show that test results indicating a fetus is at high risk for a chromosomal condition can be a false alarm half of the time. And the rate of false alarms goes up the more rare the condition, such as Trisomy 13, which almost always causes death.False alarm half the time. I really have no issue with these tests IF they were presented to doctor and patient properly. In an ideal world, abortion would not be an option, but early intervention would. In other words, if a genetic anomaly was indicated in a screen, a more accurate diagnostic test would be performed, and then a healing intervention like gene therapy would be attempted. Obviously gene therapy in utero is not yet a therapeutic option for the unborn, but when it is, these screening tests will be a valuable tool. But if companies are presenting these screens to be as good or better than a diagnostic test, doctors believe them and parents are aborting as a result, then the companies are seriously negligent. Like in this case, which turns my stomach: And at Stanford University, there have been at least three cases of women aborting healthy fetuses that had received a high-risk screen result.Obviously no child should be aborted for any reason. But this report is very troubling. How many healthy babies have been ripped from their mother's wombs because of predatory marketing? Here are my recommendations: 1. Never confuse a screening test with a diagnostic test. Always get a confirmation with an FDA approved diagnostic test. 2.Get genetic counseling with any positive genetic test, prenatal or otherwise. Request genetic counseling even if your doctor does not suggest it. Doctors often do not know about the intricacies of genetic testing, especially if the tests are new. Genetic counselors are professionals who are up on all the latest genetic tests and will surely know the difference between a screen and a diagnostic test. They are there to guide patients through the maze of genetic testing. I highly recommend availing yourself of their services. Monday, August 12. 2013Researchers Say They’ve Found Genes That Signal Risk of Autism
Autism researchers at the Autism Center of Excellence in San Diego have found a network of genes that they say signal a risk of autism. A blood test for this “genetic signature” for children as young as 1 year old is in development.
From News.com.au: A GENETIC “signature” of autism in babies as young as 12 months has been identified for the first time, an international conference is to be told.Continue reading at LifeNews >> Thursday, June 6. 2013Supreme Court: Legal to Take Your DNA if You are Arrested
This week the Supreme Court decided that it is not a violation of the 4th Amendment for law enforcement to take a DNA sample from people who are arrested. The Court said that a cheek swab was no different than mug shots or fingerprinting; its purpose is to identify the person in custody. From the New York Times:
The police may take DNA samples from people arrested in connection with serious crimes, the Supreme Court ruled on Monday in a 5-to-4 decision.The court was deeply divided with four of the justices realizing that these DNA samples were for more than just identification. They were a fishing expedition for suspects in cold cases. Scalia wrote the dissent: Justice Antonin Scalia summarized his dissent from the bench, a rare move signaling deep disagreement. He accused the majority of an unsuccessful sleight of hand, one that “taxes the credulity of the credulous.” The point of DNA testing as it is actually practiced, he said, is to solve cold cases, not to identify the suspect in custody.You may ask why this was even an issue since people who get arrested must be bad people right? Not necessarily. Do not equate being arrested with being convicted of a crime. For those convicted, taking a DNA sample is more than appropriate and an important tool for solving unsolved crimes. But just being arrested is wholly another thing. Many people are arrested for crimes they did not commit. This was a bad decision for many reasons. First, Scalia is right. A DNA sample goes way beyond simple identification. That sample has information in it that the government does not have any business knowing about unless you are actually convicted of a crime. Try getting paternity, health or "criminal gene" information from a mug shot or fingerprinting. Second, this overloads an already overloaded system. As this Washington Post piece points out: A Department of Justice study estimated that around 900,000 requests for biological screening, mostly DNA testing, were backlogged nationally at the end of 2009, the most recent year for which data is available. Meanwhile, large numbers of kits from routine arrests may be making the problem worse, argued Brandon Garrett, a professor at University of Virginia School of Law.Garrett is right. Forensic DNA testing looks at short sequences that are repeated over and over. These repeated regions are called short tandem repeats or STRs. The places where these STRs occur are called loci. There are many variations in the lengths of STRs (I may have 5 repeats at a particular loci and you may have 8 ) and by looking at many different loci scientists create a kind of profile or human bar code that is unique to each individual. This technique is also used to determine parentage because you inherit half of your unique barcode from your mother and half from your father. ![]() STR Data The problem comes from the fact that most DNA from a crime scene is not perfect. It can be degraded or mixed with DNA from other individuals. Sometimes labs can only match 9 loci to the DNA found at a crime scene. Scientists are starting to question this assumption that 10-13 loci are enough to rule out the possibility of a random match to DNA other than the suspect. In other words, if 10-13 loci are not enough to make a definitive barcode, then a 10-13 loci DNA profile can actually match more than one individual. According New Scientist, a recent look into the possibility of random matches produced some serious results: The first clue that something might be amiss came in 2005, when limited data was released from the Arizona state database, a small part of CODIS. An analyst who compared every profile with every other profile in the database found that, of 65,493 profiles, 122 pairs of profiles matched at nine out of 13 loci and 20 pairs matched at 10 loci, while one pair matched at 11 loci and one more pair matched at 12 loci. "It surprised a lot of people," says signatory Bill Thompson of UCI. "It had been common for experts to testify that a nine-locus match is tantamount to a unique identification."So in a sample of 65,000 profiles, 122 profiles matched at 9 loci, 20 profiles matched at 10 loci, and 1 profile matched at both 11 and 12 loci. According to Bill Thompson, experts have testified that 9 loci is enough for a unique profile. This comparison calls into question the assumption that 9-13 loci are enough to definitively match a suspect's DNA to that found at a crime scene. And the more people law enforcement adds to this database, the more likely a false positive will result. Taking the DNA of arrestees does indeed "dilute the databases and weakens their power." This ruling also makes the assumption that if you are innocent when arrested you have nothing to worry about. It assumes that forensic labs never make mistakes or never perpetrate fraud. Unfortunately that is not the case. Just last year a scientist in the Department of Public Health Lab in Massachusetts admitted to falsifying data in thousands of cases. The Scientist reported: The results from roughly 34,000 criminal drug cases were put into question earlier this year, when forensic chemist Annie Dookhan at the shuttered Department of Public Health Lab in Massachusetts was discovered to have falsified records on samples she was assigned to process. Instead, she forged signatures and did not perform tests she recorded as complete, according to investigations. Suspicions may have first arisen due to her impressive output—she claimed to have processed 9,000 samples in a year, whereas colleagues only averaged around 3,000. As a result of her actions, a number of defendants may have been wrongly imprisoned, while others who may have been rightly accused were freed.Scientists are people too. We make mistakes and sometimes we commit fraud to further our careers. The power of DNA testing for forensics should be limited. DNA databases should consist of samples from those convicted of crimes not clogged with samples from anyone who has ever been arrested. The chances for misuse are just too great. Besides the 4th Amendment is supposed to protect us from "unreasonable searches and seizures." I think taking DNA from those not yet convicted of a crime qualifies. Tuesday, January 15. 2013Right to Consumer Genetics?
These days it seems we have a "right" to everything except the rights that are actually given to us by our Creator and enumerated in the Constitution. (My latest favorite is the "right to be unlimited." A right for iPhone5 users according to Sprint.) Chelsea Zimmerman over at Reflections of a Paralytic sent me this article from the MIT Technology Review over the Christmas holiday. It says we have a "right to consumer genetics."
What exactly is consumer genetics? Well, you can go about getting your genes tested in a couple of ways. Your doctor can order a test for a genetic predisposition for a particular disease. You give a blood sample or a sample of cheek cells and a clinical genetics lab tests that for the mutation of interest. (That was my job.) Your doctor, or genetic counselor, gets the results and interprets them for you. Or you can, without your doc's involvement, spit in a cup and send your saliva to a for-profit company like 23andMe which will test your DNA for all kinds of things like ancestry (where they tell you what percentage of Neanderthal DNA you have) and health (where they tell you the percentage chance you will get Alzheimer's or diabetes etc.) And you can enter your spit into research projects for cancer or Parkinson's disease. With this kind of genetic testing though, you are left to try and interpret the results yourself. Continue reading at Creative Minority Report >> Tuesday, December 4. 2012Gene Patents Finally Make it to the Supreme CourtSo the long and twisted court battle over the patenting of genes is finally going to the Supreme Court. The American Civil Liberties Union (ACLU) has rightly sued Myriad Genetics and the US Patent Office over the granting of patents on naturally occurring human genes. DNA represents the physical embodiment of biological information, distinct in its essential characteristics from any other chemical found in nature. It is concluded that DNA’s existence in an ‘isolated’ form alters neither this fundamental quality as it exists in the body nor the information it encodes.Of course Myriad appealed and the appellate court came back with a ridiculous ruling that DNA isolated from the body was fundamentally different than it was inside the body so it qualified as an invention. The case then went to the Supreme Court, without hearing arguments, who kicked it back down for reconsideration. The lower court again, out of its mind, found that isolated DNA from the human body was a patentable invention. Now the highest court in the land has finally agreed to hear arguments over what I believe is the systematic claim of ownership of the human body. As someone who has isolated more DNA from people than you can imagine, I have a suggestion for the ACLU lawyers. Myriad, a company that tests women for variations in the "breast cancer genes" BRCA I and II, is claiming that isolated DNA is so fundamentally different that it is in the body that it is something they can own. If I were a lawyer for the ACLU, I would ask Myriad whose name goes on the tube of isolated DNA. Guaranteed the patient's name is on the tube. In fact, a good lab will have two patient identifiers on every tube, the patient's name and a number assigned to their sample. If isolated DNA is fundamentally different from it is in the body that it becomes a patentable invention, then why would Myraid bother to identify the sample at all? Why not just put "Myriad" on every tube and call it good? Tuesday, October 2. 2012Genetic test developed for autism
Here I go jumping into the fray. I told myself I would never do it, and here I go. I cannot tell you how many times I have been asked about autism and vaccines, especially vaccines made with cells that originated with an aborted baby.
I have always answered these questions privately, never discussing them on this blog, because I know my opinions would certainly be misunderstood and misrepresented. I am not a doctor, I am not an expert on autism, I have never conducted research on autism and so my opinion has always been my opinion and I have kept it to myself. So what do I say when people ask me if I think vaccinations cause autism? I say, in my very, very humble opinion, that I think it is too early to tell and it would be unwise to jump on that bandwagon without more evidence. Just because A seems to be link with B, does not mean that A causes B. It could be that B causes A. There could be another unknown factor C that, unseen, is the real cause of A. A being correlated with B is not good enough to prove that A causes B. As one very astute and funny man pointed out, just because you see tall people play basketball does not mean that playing basketball makes you tall. Why do I say that faced with data that autism is on a dramatic rise? Because, while autism diagnosis is on the rise, I am not sure that cases of autism are on the rise. Thirty years ago my little brother was demonstrating some pretty bizarre behavior. Our general practitioner was no help. Today even a lay person could have looked at my brother and diagnosed obsessive-compulsive behavior, but back then it was a mystery. To some extent I think the same thing is happening with autism, especially the mild cases. Thankfully, autism awareness has increased greatly, but that means more children are likely to be diagnosed. Is it possible that the increase in autism is an increase in diagnoses and not cases? It could be. What about the argument that children with autism are normal until they get vaccinations and then they suddenly show symptoms? Here I can only rely on my experience testing for a "Pervasive Developmental Disorder" (often known as "Autism Spectrum Disorder") called Rett Syndrome. In Rett Syndrome, a girl (boys usually do not survive Retts) seems normal in her development until about 12 to 18 months. Then she regresses and loses the ability to speak or walk. We know that Rett Syndrome, in a majority of cases, has a genetic component, a mutation in an important gene on the X chromosome, that she had well before her symptoms began. But without this information would it not be easy to assume that the shots she got at the doctor caused her regression? It might. It is my non-expert opinion that autism is complex. So complex that the cause it not likely as simple as a vaccination. I have always had the opinion there is a genetic component that, like in Rett Syndrome, may begin to show itself around the age of 2. That being said, Australian researchers announced they have developed a test for several genetic markers associated with autism, giving them, they say, the ability to predict autism 70% of the time. From Disability Scoop: Genetic testing for autism is one step closer to reality, researchers say, a development which may open the door for earlier diagnosis.Does this prove autism has a sole genetic cause? No because again, genetic markers correlated to autism does not mean these genetic variations cause autism, they are just associated with autism. There still maybe an unidentified environmental component. That component maybe vaccination sensitivity. Again, I think it is too early to tell and more research is needed taking into account a possible genetic predisposition. But I think the good news here is that researchers are on the trail of autism and will hopefully soon capture and wrangle this monster to the ground. Tuesday, September 25. 2012Moms Say Too Much Prenatal Genetic Info is "Toxic"
"TMI! Mom. TMI!" I hear that phrase a lot with a couple of teenagers in my house. TMI, of course, is short for Too Much Information.
A new study is showing that there is such a thing as TMI in prenatal testing. Now I am a proponent of prenatal genetic testing when it is appropriate for the health and well-being of the child. I think it is a powerful tool that proves beyond a shadow of a doubt that a distinct human life is growing inside the womb. Just because abortion-on-demand (the real killer of the unborn) is the law of the land does not mean prenatal testing is inherently evil. But there is such a thing as too much information, especially if that information has no clinical value. There is a lot about genetics that remains a mystery. Just because a genetic anomaly is found does not mean doctors know what that anomaly means if anything. A new type of genetic testing called micro-array testing looks at a person's entire genome (all of their DNA) looking for abnormalities. It is a powerful tool for doctors who have a child with unexplained developmental delay or other undiagnosed problems. But for an unborn child, a micro-array analysis may reveal genetic abnormalities that have no clinical significance, meaning that scientists do not know if these genetic anomalies will cause problem or what those problems might be. Not all chromosomal differences cause disease. And telling mom about her child's results that have uncertain clinical significance just makes her stressed out and anxious. Researchers at Perelman School of Medicine at the University of Pennsylvania asked mothers who got ambiguous results through micro-array how they felt about them. The moms called the results "toxic knowledge." Continue reading at LifeNews >> Tuesday, August 28. 2012Does the State Have Your Child's DNA?
I hate to be so sensational, but I think it is important for parents to understand that your child's DNA maybe stored in a state government facility and you have no idea.
Impossible you say? You know that heel stick that your child got in the hospital right after birth? Some states keep and catalog that blood for use in further research and some envision a time when a whole genome scan is performed on that sample. Nature recently called the information stored on these cards a genetic "jackpot" and there are scientists who would love to be given access to that treasure trove. In addition, there are real concerns that the information provided by that seemingly innocuous heel stick could be used to usher in a new era of eugenics. Continue reading at Creative Minority Report >> Wednesday, August 1. 2012Fighting against prenatal testing is counterproductive
Maybe because I have chosen genetic testing as a profession, I am reluctant to blame prenatal testing for the mass eugenic abortion that occurs in our modern society. I see great potential in protecting and treating the unborn with every new advance.
I often argue that it is the abortion that kills not the information provided by testing and pro-lifers are getting distracted by every new advance in prenatal testing taking our eye of the real moral evil: abortion. It is dangerous, and frankly wrong, to spend our efforts on restricting access to prenatal testing and the information it provides instead of continuing to tackle the abortion industry. I think a good analogy would be assisted suicide. If assisted suicide was legal all over the United States and rampant among those who get terminal diagnosis, would we urge doctors to stop giving out terminal diagnoses to solve the problem? Of course not. We would work toward changing legislation to restrict assisted suicide and work to support those who have received a terminal diagnosis. Sometimes I feel alone in the pro-life community as the only one who doesn't get upset at the news of yet other prenatal genetic diagnostic tool. That was until I read this awesome piece by Dr. Gerard Nadal. In response to the many e-mails he got from his readers about early genetic prenatal testing from a simple maternal blood sample, he wrote this: We live in the age of Molecular Biology, where diagnostics (including those for Down Syndrome) are becoming much more accurate, sensitive, and inexpensive. It’s a blessed thing to behold.Thank-you Dr. Nadal. I no longer feel so alone! Wednesday, June 27. 2012New Prenatal Genome Test Doesn't Kill, Abortion Still Does
I was not going to write about this new development in prenatal genetic testing for a couple of reasons. First because I have written about this technology that allows a peek into the womb from a maternal blood sample before. And second because I feel I have said what I am going to say so many times that I feel some poor dead horse somewhere will get an unnecessary beating.
I am sure you have seen the news already. Scientists at the University of Washington have put together the entire genome of an unborn baby using only a maternal blood sample, with minute fragments of fetal DNA, and a paternal saliva sample. From DiscoveryNews: In a development scientists are calling a "tour de force," researchers have reconstructed the genome of a fetus using DNA samples from the parents.... I feel compelled to write about this I am seeing the pro-life side once again slide into the rhetoric of how awful this technique is. It will naturally lead to more abortions and therefore is inherently evil. Tuesday, May 22. 2012Scientists use genetic testing in search of Bigfoot
They are on your trail Harry and not even the Hendersons can protect you. From Reuters:
Scientists are turning to genetic testing to see if they can prove the existence of the elusive hairy humanoid known across the world as bigfoot, yeti and sasquatch. Friday, April 13. 2012Study finds genetic testing not good at predicting disease
If you have been reading this blog for any length of time you know that I despise genetic determinism. What exactly is genetic determinism? It is the unfortunate belief that we are no more than what is coded in our genes and that we can be evaluated as individuals accordingly.
I despise genetic determinism not simply because it reduces the dignity of a human person down to a sequence of nucleotides, but also because it is wrong scientifically. In reality, very few traits or diseases can be directly linked to a single gene variant or mutation. Some diseases are definitively linked to a specific problem in a gene or genes, examples would be Tay-Sachs, Sickle Cell Anemia, Cystic Fibrosis and Huntington's. But the truth is that for most other diseases, it is just not that simple. Environment has as much or more to do with disease onset and progression as does genetics. In fact, a recent study done by researchers at Johns Hopkins showed that genetic testing for disease is really not that predictive. They looked at occurrence of disease in identical twins and found that genetics were not a good predictor of who will suffer from what disease. From The Atlantic": The just-published study examines how often identical twins get the same diseases. Reviewing records of 53,666 identical twins in the United States, Sweden, Finland, Denmark, and Norway, researchers tabulated how well genes predict the chance of getting a disease. The answer is that they really can't. Predictions based on genes turned out to be very close to useless. As Gina Kolata summed up in The New York Times: "While sequencing the entire DNA of individuals is proving fantastically useful in understanding diseases and finding new treatments, it is not a method that will, for the most part, predict a person's medical future."And yet, at the same time utilitarian ethicists are continuing to push the idea that parents have the obligation to use IVF and preimplanatation genetic diagnosis (PGD) to have healthier children. In PGD, a single cell is taken from the early embryo and is tested for as many as 6000 different genetic variations. The embryos that make the genetic cut get a chance at being transferred to their mother's womb. The others are discarded, donated to research or put in the deep freeze. BioEdge reports that a new paper in the American Journal of Bioethics argues that parents are not just encouraged, but should be OBLIGED to use PGD to have "healthier" children. The title of the paper is "The Case for a Parental Duty to Use Preimplantation Genetic Diagnosis for Medical Benefit" and here is the abstract: This article explores the possibility that there is a parental duty to use preimplantation genetic diagnosis (PGD) for the medical benefit of future children. Using one genetic disorder as a paradigmatic example, we find that such a duty can be supported in some situations on both ethical and legal grounds. Our analysis shows that an ethical case in favor of this position can be made when potential parents are aware that a possible future child is at substantial risk of inheriting a serious genetic condition. We further argue that a legal case for a duty to use PGD for medical benefit can be made in situations in which potential parents have chosen to conceive through in vitro fertilization and know that any children conceived are at substantial risk of having a serious genetic condition.They argue there is a LEGAL obligation for parents who know they carry a serious genetic mutation to use PGD. Right now these ethicists argue an obligation to use PGD for a serious genetic condition, but as another utilitarian ethicist, Julian Savulescu, has already argued, some ethicists believe parents use of PGD should go beyond disease traits and be expanded to personality traits like intelligence as well. Now realize that PGD chooses which children get to live based simply on their genetics. A criteria that the researchers at Johns Hopkins decided is not very predictive in disease. Which means genetics is not likely predictive in other personality traits like intelligence either. Environment is important in shaping a person both medically and socially. But the IVF embryo has yet to experience much environment. It seems the utilitarian ethicist really doesn't care. They want a nice neat genetic package with which they can arrange humanity into little boxes labeled "fit" and "unfit." I think there was a pernicious movement of the early 20th century (starts with an E and ends in UGENICS) that did the same. Remember where that lead. As The Atlantic points out: We could clone Einstein and we really don't know if he's going to turn out to be an Einstein. Tuesday, March 27. 2012US Supreme Court rejects gene patents
For 30 years, the U.S. Patent Office has been issuing patents for naturally occurring genes. About a fourth of our genes are patented by companies who are looking to make a profit off of a molecule we naturally make in our bodies. Objects of nature are not patentable so genes should not be patentable either. As the late Michael Crichton pointed out, issuing patents for naturally occurring genes is like issuing a patent for noses. Such a patent would allow a company to restrict or charge royalties for any product like glasses, sinus medication or sunscreen that has anything to do with noses.
I believe gene patents are not just a legal issue, but a moral issue. The patenting of genes allows what I believe to be an unethical practice: the systematic claim of ownership of the human body. You own your DNA while it is in your body, but if someone extracts it and identifies the purpose of it, they now own it. Even though it is still your DNA from your body. This naturally reduces the human body to pieces that can be bought and sold. John Paul II, in an address to the Pontifical Academy of Sciences on genetic research, stated: On this subject, we rejoice that numerous researchers have refused to allow discoveries made about the genome to be patented. Since the human body is not an object that can be disposed of at will, the results of research should be made available to the whole scientific community and cannot be the property of a small group.Gene patenting affects you directly whether you know it or not. Because a company legal "owns" a gene sequence, they control who is able to test or research that gene. In the case of genetic testing, labs are limited on what genes they can offer tests for because of gene patents, which limits the choices they can offer patients. Labs that are allowed to test a patented gene pay royalties to the companies that own the genes which drives up the cost of the genetic test. Many labs, like ones I have worked in, just chose not to offer the test at all. These patents also allow companies hold patents on genes and not do research on those genes. They can also not allow others to do research either. And because so many diseases have a genetic component, gene patents tie the hands of researchers who want to look at genetic links to disease. As Dr. Iris Schrijver, president of the Association for Molecular Pathology, which is against the issuing of gene patents, observed: Because variation in gene sequences plays an important role in the development and progression of many diseases, through gene patents patent holders can essentially gain ownership of the understanding of some diseases and of certain areas of patient care itself.In the case of some genes like the breast cancer genes BRCA I and BRCA II, one company, Myriad, owns the gene and only Myriad offers the test for variations that signal a high risk of breast or ovarian cancer. This means that if a patient wants a second test run by another company to confirm the test result and test interpretation before they have radical surgery, they are out of luck. In addition, many women who fear that they are at risk simply cannot afford the $3000 test that could give them the information to save their life. And because of gene patents, they cannot go anywhere else. To put a human face on gene patents, I once got a call from a frantic father whose daughter was diagnosed with Long QT, a rare and serious genetic heart condition. He and his wife were faced with putting their 4 year-old little girl on serious medication and fitting her with a pace maker because of the genetic testing results showed she had a rare genetic mutation for Long QT. Something about the lab that gave them their results did not sit right with them. Before initiating the invasive procedures on their daughter, they wanted a second opinion. The could not get one without traveling overseas because only one lab in the United States owned the patent for the gene and only they offered the test. The ACLU and the Association for Molecular Pathology have sued Myriad Genetics and the U.S. Patent Office over Myriad's patent on the BRCA I and II genes. The initial ruling, issued by Judge Sweet, was that DNA isolated from its natural environment cannot be patented. Of course Myriad appealed the ruling. Then a higher court that deals with patent cases overturned Judge Sweet's ruling saying that DNA isolated from the body to be tested was remarkably different that the DNA found in the body. I found this decision ludicrous. I have isolated DNA from thousands of patients and never once did I think it didn't contain the same information as DNA inside their bodies. If I did think that isolated DNA was so different from DNA inside the body that it was a patentable invention, I wouldn't bother testing it. This case then went to the Supreme Court. The Supreme Court has rightfully overturned the stupid decision that human DNA outside the body was remarkably different than inside the body and sent the case back down to the lower court to be reconsidered. The high Court cited another ruling that they made last week that laws of nature are unpatentable. This is good news. One step closer to making the patenting of our genes invalid. Now let's hope that the lower court gets the decision right this time. Tuesday, March 6. 2012Oregon Couple Sues over Misdiagnosis of Down Syndrome in their Daughter
A couple in Portland are suing Legacy Health because their child has Down Syndrome. This is another of these so-called wrongful birth lawsuits that are so very wrong.
The wrongful birth suit is brought by the parents of a sick or disabled child against medical professionals that, the parents say, were negligent. The wrongful birth lawsuit does not say that the medical practitioners caused the disease or disability, which would be a valid reason to sue. Instead the wrongful birth lawsuit claims the that doctor failed to inform the parents of the illness or disability of the child and that had they known, they would have aborted their child. In other words, the parents are saying we wish our child was dead. Because he or she is not, someone has to pay. The parents often use the excuse that they love their child; they are simply suing to acquire funds to care for their sick or disabled offspring. But to get those funds they have to insist that, had they known, they would have killed that very same child. The Oregon couple is suing for $7 million. From ABCNews: The parents of a four-year-old Oregon girl with Down syndrome are suing Legacy Health in Portland because they say doctors misdiagnosed their daughter as not having the condition during a prenatal screening. There is much confusion over prenatal testing in general so it is not surprising that the details of exactly what testing was perform have been omitted. People often confuse a screening method called a triple or quad screen that simply looks at protein levels in a maternal blood sample and actual genetic testing of the fetus through amniocentesis or chorionic villus sampling (CVS). While the quad screen is just that, a non-invasive screen that requires further testing, the genetic testing through amnio or CVS is much more accurate because it tests the DNA of the baby directly. Monday, November 14. 2011Wrongful Life Suits on the Rise in Israel
In genetics, being Jewish is not a religious preference but an ethnicity. Clinical genetics labs won't ask you if you are Christian, Muslim, or Hindu, but they will surely ask you if you are Jewish. Why? Because for many reasons including societal pressures and internal preferences, Jews have been intermarrying with other Jews for hundreds of years. One particular subset of Jews called Ashkenazi Jews are descended from Jews in the Rhine area of Europe. Ashkenazi Jews are surprisingly genetically homogeneous and now make up 80% of all Jews worldwide.
Unfortunately, Ashkenazi Jews are carriers for some pretty devastating genetic disorders, including Tay-Sachs, cystic fibrosis, Faconi anemia and even breast and ovarian cancer. Often they do not know they are carriers until they meet someone that carries the same genetic mutation and have children who then have the disease. There is a movement in the Jewish community to get young people screened before they marry so they can make a more informed choice about their life partner. In fact some labs, offer a panel of genetic tests just for Ashkenazi Jews. The other approach to genetic carrier testing is to only test pregnant women. If the woman is a carrier, then the father is tested. If he is also a carrier, then the fetus is tested to see if it has the genetic disease. This is the approach prevalent in the United States and in my opinion totally backwards. If there is already a life growing in the womb, the genetic testing to prevent him or her from inheriting the disease is too late. But apparently some parents in Israel do not think it is too late. Wrongful-life suits are becoming more common among Israeli Jews. What is a wrongful-life suit? It is a suit brought by the parents, on behalf of the child against medical professionals that argues that if the family had known the child had a genetic disease, he or she would have been aborted. The family sues for monies to care for the sick child that they insist never should have been born. The sickness of wrongful life lawsuits is not the illness of the child, it is the audacity of parents to say that if they had known they would have killed their child, even if it is for money to pay for care. And this is what is happening with more frequency in Israel. From BioNews: Increasing numbers of Israeli children with birth defects are suing medical professionals for failing to detect abnormalities and allowing them to be born, says the New Scientist. The magazine reports that such is the Israeli Government's concern over the rise in 'wrongful life' lawsuits it has launched an investigation into the validity of the claims.The ramifications of wrongful life suits are tremendous. First, these children do not have a genetic disease because of negligent doctors. The children inherited the disease from the very people bringing the lawsuit, the parents. If the doctors caused disease or harm to the child, then a lawsuit would be appropriate, but that is not the case with these suits. This mentality that a doctor could be held accountable for an already existing condition puts them in an awkward and difficult situation where they are more likely to over test and possibly cause healthy children to be aborted: Concerns have also been raised over the effect of the increasing number and value of claims against the medical profession. 'Physicians are increasingly practising defensive medicine, and doing a lot of testing', said Rabbi Steinberg. 'But more testing means more false positives – and that means more abortions, because geneticists don't always know if results indicating the possibility of chromosomal abnormalities are meaningful'.And finally, what about the psyche of the child? I think hearing that your parents would have preferred you dead would be much more damaging than any genetic disease: The psychological implications of the lawsuits on the children concerned have been highlighted by several medical ethicists. 'I find it very difficult to understand how parents can go on the witness stand and tell their children 'it would have better for you not to have been born. What are the psychological effects on the children?' said medical ethicist Professor Rabbi Avraham Steinberg of University Hadassah Medical School, Jerusalem.Wrongful life suits are beyond insidious. They are a product of a world that believes preventing genetic disease means killing those that have it. Totally backward and totally evil. Wednesday, September 21. 2011Be Not Afraid and 1heart2souls providing support for parents after prenatal diagnosis Over the years I've received many emails from women who aborted, terminated or induced early their Trisomy 13 children. They were amazed and completely surprised that their child could have survived, or at least grown to a point where they could reach their mothers arms! These women were given NO HOPE that their child would make it to term. Many were even told that their child’s diagnosis was more severe than the norm and discouraged from researching the disorder for themselves. Without a full understanding of this complex disorder, they felt they had no option but to terminate with all the pressures around them. These women fall into a unique category, those who felt "pressured to interrupt their pregnancy for medical reasons." Another mother, Katie, wrote this about her treatment by medical professionals after a prenatal diagnosis of Trisomy 13: We had chosen to have a termination due to all the pressure from the doctors/genetic counselors/professionals. Also at that time it was all we knew to do. No one gave us any information and we had no access to viable information.... Dr. Richard W. Sams II, a family physician in the United States Navy and the director of the Naval Hospital Jacksonville Family Medicine Residency Program, relayed the experience of one of his patients in an article for The New Atlantis journal: One woman for whom I provided prenatal care had a child diagnosed with a severe heart anomaly by ultrasound at 20 weeks gestation. The anomaly is virtually always lethal. Both a perinatologist and a geneticist recommended to the couple that the woman have an abortion. Despite being deeply offended by the recommendation and informing the physicians that she would carry the child to term, the suggestion was repeated numerous times. Her experience is far from anomalous.
1heart2souls is an organization formed to support expectant parents who will experience infant loss or the birth of an infant with disabilities. Gray says that over 98% of babies with a poor prenatal prognosis are aborted. Another great resource that has been around for many years is Be Not Afraid. At their website you can find all kinds of resources for just about any prenatal diagnosis. And it is also a great place for genetic counselors as well who want to provide more than just abortion referrals. Karen, a genetic counselor, wrote the following about Be Not Afraid: "Genetic counselors are frequently the providers that break the initial news to parents about their baby. It’s not easy for parents to hear this "news" - it is a life-altering and critical time and they feel all the weight of the world upon their shoulders. I always consider the time I spend with them a true privilege. Every story is different, but each one deeply moves me, especially when I am allowed to enter into their lives. In them I see that that unconditional love only a mother and a father can have for their baby despite knowing their baby has serious birth defects, some of them life threatening. We cannot do this alone. Be Not Afraid Ministry has been an instrumental resource because they bring a higher level of care and support to these families. I feel truly indebted to them." These two organizations remind us all that there is no hope in abortion, only death. Parents do have other options and places to turn if they are being pressured to abort their child because of a prenatal diagnosis. Saturday, August 13. 2011Early sex determination test turns an embryo into a boy or girl No longer just an embryo, but a boy or girl. Photo: Westside Pregnancy Clinic At the news, there was a collective groan from both sides of the abortion debate. Prolifers and prochoicers alike realize that this test will make sex selective abortions much easier. I am encouraged to see that both sides realize that this is bad. But as usual many people, whether they realize it or not, lay the blame for the sex selective abortion on the test and not on the abortion. My readers know that I will not do that. Is there something inherently wrong with using a non-invasive test to find out the sex of your baby at 7 weeks? Of course not. (Unless you are getting the test with the intent to abort.) There is nothing wrong with being curious about the life you have growing inside you. In fact this test allows what was once called an "embryo" to now be called a "boy" or "girl." It further humanizes what has previously been dehumanized. I believe the sooner we can relate to the life growing inside the womb the better. I will be radical and say that because they inherently show us that the life inside the womb is indeed a human being with a distinct genetic make-up, such early prenatal tests may prevent more abortions than they "cause." It is the abortion that kills, not the testing. Many would like to limit access to early prenatal testing. I understand that as a practical way to protect life in the womb in world where there is abortion on demand and begrudgingly support that. But I cannot shout it from the roof tops enough: the problem is the abortion not the testing. I feel blaming the test for sex selective abortion is somewhat like a white flag. As if unconsciously we are acknowledging that abortion is a permanent fixture in our society so the only way to fight it is to label other things that may lead a woman to abort as the problem. I will not do so. I may stand alone but I lay the blame for sex selective abortion on the abortion. Abortion is the procedure that kills. It is the abortion that taints every prenatal test from ultrasound to amniocenteses and now this early blood test. Imagine a world without abortion. In such a world we would be rejoicing about technology that lets us peek inside and find out more about the boy or girl (no longer just an "embryo") in the womb without putting their life at risk. I refuse to the raise the white flag and will say that the only way to ensure that sex selective or eugenic abortions do not take place is not to point a finger at prenatal testing, but to get rid of the evil that is abortion. Monday, August 1. 2011Court Rules that DNA Patentable if Removed from Your BodyFor decades the U.S. Patent Office has been issuing patents for naturally occurring genes. This affects you directly whether you know it or not. Because a company legal "owns" a gene sequence, they control who is able to test or research that gene. In the case of genetic testing, labs are limited on what genes they can offer tests for because of gene patents, which limits the choices they can offer patients. Labs that are allowed to test a patented gene pay royalties to the companies that own the genes which drives up the cost of the genetic test. Many labs, like ones I have worked in, just chose not to offer the test at all.
The U.S. Department of Justice agreed: "...the unique chain of chemical base pairs that induces a human cell to express a BRCA protein is not a ‘human-made invention.’ Nor is the fact that particular natural mutations in that unique chain increase a woman’s chance of contracting breast or ovarian cancer. Indeed, the relationship between a naturally occurring nucleotide sequence and the molecule it expresses in a human cell – that is, the relationship between genotype and phenotype – is simply a law of nature. The chemical structure of native human genes is a product of nature, and it is no less a product of nature when that structure is ‘isolated’ from its natural environment than are cotton fibers that have been separated from cotton seeds.” Of course Myriad appealed the ruling. Last week the appellate court ruled for Myriad and stated that genes CAN be patented because isolated DNA is fundamentally different than DNA in the body. From the New York Times: “The claims cover molecules that are markedly different — have a distinctive chemical identity and nature — from molecules that exist in nature,” Judge Alan D. Lourie wrote for the court. I find this ruling to be ridiculous and this is why. I have personally isolated DNA from thousands of patients for genetic testing. I find the ruling that all that DNA I isolated is so fundamentally different that it is eligible for a patent laughable. Is the DNA I isolated still have all of the proteins that surround it naturally? No. It is in the same shape that it was when it was in a white blood cell? No. Is it still in a continuous piece? No. Is it still a naturally occurring molecule that has information about the organism from which it was isolated? Absolutely!!! On this subject, we rejoice that numerous researchers have refused to allow discoveries made about the genome to be patented. Since the human body is not an object that can be disposed of at will, the results of research should be made available to the whole scientific community and cannot be the property of a small group. Tuesday, June 14. 2011State supported eugenics in France?It has been estimated that 96% of fetuses with Down Syndrome in France are aborted. Most of the cases are detected in older women whose physicians offer prenatal testing. As in the United States, offering prenatal testing for Downs in France is not a government mandated practice for obstetricians. The American Congress of Obstetricians and Gynecologists simply recommends that doctors offer it. Lawmakers in France are considering making it mandatory for physicians to offer prenatal testing for Down Syndrome. Why is this significant? Because mandating that doctors offer prenatal testing completely changes the game. It is not that the prenatal testing is inherently evil. In most cases it is simply a way to get more information about the life growing inside the womb. It is what is done with that information that is problematic. Abortion on demand complicates the entire prenatal testing arena. Without legalized abortion, the use of prenatal testing would be naturally limited to conditions that could benefit from some kind of prenatal intervention. Abortion takes information that may or may not be clinically useful and makes it deadly. Many Catholic hospitals and pro-life doctors all over the world have limited access to non-clinically useful prenatal testing (like testing for the sex of the fetus) to try and protect life in the womb in a world where abortion on demand is a reality. Mandating that all doctors offer prenatal testing takes away that discretionary ability. And with a 96% abortion rate for fetuses with Down Syndrome, a mandate for offering prenatal testing, even to young woman who are at a lower risk of having a child with Downs, amounts to a de facto state sponsored eugenics program. At this point there is no treatment for Down Syndrome in the womb. If there was, a mandate to offer testing would be an entirely different story. But since there is not, coupled with the outrageously high abortion rate of Down Syndrome fetuses, this proposal smacks of a government sanctioned seek-and-destroy mission against those with an extra chromosome 21. The Jerome Lejeune Foundation is a leader is funding research that is aimed at understanding the function of chromosome 21 and normalizing intelligence in those with Down Syndrome. They are leading the charge in preventing France from implementing this mandate. From their website:
They ask that you sign the above petition to protect the lives of those with Down Syndrome here. The page is in French. Just click on the big red "Signer" button on the top right and then enter your information.
Friday, November 12. 2010Where the Catholic Church and Obama's Department of Justice AgreeIs there an issue where the current federal administration and the Catholic Church agree? Yes. The granting of patents for naturally occurring human genes. Many people are not aware that about 25% of all human genes are patented. This means that a company or university owns the genetic code that makes up that gene. They own genes that you have and use in your body everyday. You may be surprised to find out that the patenting of your genes affects you directly. Because a company legal "owns" a gene sequence, they control who is able to test or research that gene. In the case of genetic testing, labs are limited on what genes they can offer tests for because of gene patents, which limits the choices they can offer patients. Labs that are allowed to test a patented gene pay royalties to the companies that own the genes which drives up the cost of the genetic test. Many labs, like ones I have worked in, just chose not to offer the test at all. In the case of some genes like the breast cancer genes BRCA I and BRCA II, one company, Myriad, owns the gene and only Myriad offers the test for variations that signal a high risk of breast or ovarian cancer. This means that if a patient wants a second test run by another company to confirm the test result and test interpretation before they have radical surgery, they are out of luck. In addition, many women who fear that they are at risk simply cannot afford the $3000 test that could give them the information to save their life. And because of gene patents, they cannot go anywhere else. The ACLU has taken on gene patents and it is suing Myriad and the US Trademark and Patent Office for issuing patents on naturally occurring gene sequences. The judge in the case has agreed that Myriad's patents on the BRCA I and BRCA II gene variants are invalid. Myriad has appealed the decision. A couple of weeks ago, in an unexpected move, The US Department of Justice filed an amicus brief that essentially states that naturally occurring genes cannot be patented and that it does not support the practice. One argument for gene patents has been that isolating DNA out of its natural environment is a sufficient enough innovation to grant a patent on the sequence. The Department of Justice disagrees. From the brief:
Here is where things get interesting. The Patent Office has announced that they will continue to award gene patents even though the Department of Justice has come out against it. Once again, on the Federal level the left hand is doing exactly what the right hand says not to. I believe that patenting naturally occurring gene sequences is unethical. It is hard to find official Church teaching on gene patents, but I did find this quote from John Paul II in an address to the Pontifical Academy of Sciences: The ability to establish the genetic map should not lead to reducing the subject to his genetic inheritance and to the alterations that can be made to it. In his mystery, man goes beyond the sum of his biological characteristics. He is a fundamental unit, in which the biological cannot be separated from the spiritual, family and social dimensions without incurring the serious risk of suppressing the person's very nature and making him a mere object of analysis. By his nature and uniqueness, the human person is the norm for all scientific research. "He is and he ought to be the beginning, the subject and the object..." of all research (Second Vatican Council, Gaudium et spes, n. 25). I believe that I am interpreting John Paull II correctly by saying that is unethical to patent a naturally occurring gene. Patents should be be awarded for inventions, like novel approaches to testing or manipulating the gene, but not for the gene itself. Monday, April 19. 2010Update on gene patentsBelieve it or not there is one issue out there where the mainstream media and the Catholic Church do not collide. What is it? The granting of patents for naturally occurring human genes. You are probably not aware that about 25% of all human genes are patented. This means that a company or university owns the genetic code that makes up that gene. They own genes that you have and use in your body everyday. You also may not be aware that the patenting of your genes affects you directly. Because a company legal "owns" a gene sequence, they control who is able to test that gene or research that gene. In the case of genetic testing, labs are limited on what genes they can offer tests for because of gene patents, which limits the choices they can offer patients. Labs that are allowed to test a patented gene pay royalties to the companies that own the genes which drives up the cost of the genetic test. In the case of some genes like the breast cancer genes BRCA I and BRCA II, one company, Myriad, owns the gene and only Myriad offers the test for variations that signal a high risk of breast or ovarian cancer. This means that if a patient wants a second test run by another company to confirm the test result and test interpretation before they have radical surgery, they are out of luck. Many women simply cannot afford the $3000 test that could give them the information to save their life. And because of gene patents, they cannot go anywhere else. The ACLU has taken on gene patents and it is suing Myriad and the US Trademark and Patent Office. Here is a clip from 60 Minutes on the progress of this lawsuit: I believe that patenting naturally occurring gene sequences is unethical. It is hard to find official Church teaching on gene patents, but I did find this quote from John Paul II in an address to the Pontifical Academy of Sciences: The ability to establish the genetic map should not lead to reducing the subject to his genetic inheritance and to the alterations that can be made to it. In his mystery, man goes beyond the sum of his biological characteristics. He is a fundamental unit, in which the biological cannot be separated from the spiritual, family and social dimensions without incurring the serious risk of suppressing the person's very nature and making him a mere object of analysis. By his nature and uniqueness, the human person is the norm for all scientific research. "He is and he ought to be the beginning, the subject and the object..." of all research (Second Vatican Council, Gaudium et spes, n. 25). I believe that I am interpreting John Paull II correctly by saying that is unethical to patent a naturally occurring gene. Patents should be be awarded for inventions, like novel approaches to testing or manipulating the gene, but not for the gene itself. Hat Tip: Biopolitical TImes Tuesday, February 23. 2010Genetic testing doesn't kill, abortion doesI am reluctant to write this post simply because I greatly admire the woman who I am about to comment on. More importantly, I feel her outrage. But I feel it is important to put the blame for eugenic abortion where it truly belongs. Kristan Hawkins, a pro-life mother of a child with cystic fibrosis, writes at LifeNews.com about how prenatal genetic testing is killing babies:
I understand her anger and frustration. Having tested pregnant mothers and their partners for cystic fibrosis mutations, I am fully aware of how this information is being used. But I disagree that it is the "genetic testing [that] is killing little girls and boys like Gunner." Genetic testing may be cited as the reason to kill a baby with a genetic disease, but the REAL killer is abortion on demand. Without legalized abortion, prenatal testing would be what it should be, a way to find out more about the life going in the womb, especially if something is going wrong. Without legalized abortion, the use of prenatal testing would be naturally limited to conditions that could benefit from some kind of prenatal intervention. The problem is abortion and a medical establishment that uses it as a "solution" to medical problems. Always has been. Abortion takes clinically useful information and makes it deadly. Why do I feel compelled to make this distinction when I know that the information that prenatal genetic testing provides is being used as the reason to murder babies with genetic disorders? Because I know that someday doctors will likely able to treat genetic disease in utero. Possibly even with gene therapy. I envision a day where drugs that are currently being tested to reverse the cognitive symptoms of Down Syndrome are used in the womb to halt the effects of an extra chromosome 21. That cannot happen without an accurate prenatal genetic test. We should not equate prenatal genetic testing with murder, especially in law. If we do, we may lose valuable future opportunities to heal in the womb. I do wholeheartedly agree with Ms. Hawkins assessment of the way eugenic abortion is portrayed. Aborting a child with a genetic disease DOES NOT cure the disease. It only gets rid of the people with it. That wouldn't work with cancer, but somehow when it comes to life in the womb, death is described as a "cure." **Note: I am FULLY aware that amniocentisis (the most common way prenatal genetic testing is now performed) can cause miscarriage but that is NOT the intent of the procedure. While the very intent of abortion is to destroy the life in the womb. In the very near future, I am positive there will be ways to conduct prenatal genetic testing that is less invasive or even non-invasive.**
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