Mary Meets Dolly

Uterus Transplant Baby Lost

nospam@example.com (Rebecca Taylor) — Fri, 17 May 2013 13:27:33 -0700

This is so incredibly sad for so many reasons. There is really nothing else to say. (I have already expressed my concerns about uterine transplants here.) From the UK's Daily Mail:

A woman who was the first to have a successful womb transplant from a dead donor has had her pregnancy terminated after the embryo showed no heartbeat, doctors in Turkey have said.

Derya Sert, 22, who was born without a womb, had been receiving in vitro fertilisation (IVF) treatment after the transplant in August 2011.

Her pregnancy was announced in April.

But in a statement released today by Akdeniz University Hospital in Turkey's Mediterranean city of Antalya, it read: 'Derya Sert's pregnancy was terminated after her end of eight weeks examination showed no embryo heartbeat.

'The general health status of the patient is fine.

'IVF will be continued when she is ready, in appropriate conditions.'

I mourn the loss of this little one. Eternal rest grant unto him or her, O Lord, and let perpetual light shine upon him or her. May the souls of the faithful departed, through the mercy of God, rest in peace.

Human Embryos Created by Cloning in Oregon

nospam@example.com (Rebecca Taylor) — Wed, 15 May 2013 10:36:38 -0700

Once induced pluripotent stem cells hit the scene, human cloning slowly faded away. Why clone embryos with human eggs (exploiting women in the process) to get "patient-specific" embryonic stem cells when you can just take an adult cell and reprogram it back to an embryonic-like state? No eggs, no cloning, no creating and destroying embryos.

But I knew cloning was just hiding in the shadows waiting to resurface. Scientists are still trying to achieve this "holy grail" of human biology: the creation of human clones. Ones that will generate embryonic stem cells.

A team of scientists, including a fertility specialist (meaning IVF doc) from Japan, has done it. Not in some underground lab in China, but in the good old USA. Oregon to be exact. Nature has the story:

A paper published this week by Shoukhrat Mitalipov, a reproductive biology specialist at the Oregon Health and Science University in Beaverton, and his colleagues is sure to rekindle that debate. Mitalipov and his team have finally created patient-specific ESCs through cloning, and they are keen to prove that the technology is worth pursuing....

Mitalipov and his group began work on their new study last September, using eggs from young donors recruited through a university advertising campaign. In December, after some false starts, cells from four cloned embryos that Mitalipov had engineered began to grow. It looks like colonies, it looks like colonies, he kept thinking. Masahito Tachibana, a fertility specialist from Sendai, Japan, who is finishing a 5-year stint in Mitalipovs laboratory, nervously sectioned the 1-millimetre-wide clumps of cells and transferred them to new culture plates, where they continued to grow evidence of success. Mitalipov cancelled his holiday plans. I was happy to spend Christmas culturing cells, he says. My family understood.

Let us be clear where Nature is not. These researchers did not create "cells" they created embryos which where then destroyed for embryonic stem cells.

Nature also says these cells are "perfectly matched" to the person who donated the adult cell that provided the nucleus for the somatic cell nuclear transfer or SCNT. (For a refresher on SCNT click here.) Embryonic stem cells from a cloned embryos cannot be "perfectly matched" because there is DNA leftover from the woman who donated the egg. (The only way the ESCs created would be "perfectly matched" is if a young woman provided the eggs to create her own clone.)

Speaking of young women, did you noticed where the supply of eggs needed for these experiments came from? Young, cash-strapped, college students enticed by the $3,000-7,000 compensation. I wonder how many of these young women experienced complications from their "donation." I wonder of any will lose their own fertility as some egg donors have.

I wonder also why, with iPSC technology, anyone is even pursuing SCNT anymore. I am not alone:

Still, Daley and most other stem-cell researchers have shifted to another method for creating genetically matched, patient-specific cell lines: reprogramming adult cells to an embryonic state to produce induced pluripotent stem (iPS) cells. First reported in 2006, the technique does not involve eggs, cloning or destruction of embryos. Honestly, the most surprising thing [about this paper] is that somebody is still doing human [SCNT] in the era of iPS cells, says Miodrag Stojkovic, who studies iPS cells for regenerative medicine and runs a fertility clinic in Leskovac, Serbia.

Actually, I don't wonder. I have always thought that stem cells were a red herring. I see the end game to be reproductive cloning, or cloning-to-produce children.

Nature reports that Tachibana will publish why reproductive cloning is not possible. I would love to see that. Until today it seemed cloning for research was also "impossible." Unless the United States gets some federal legislation that bans SCNT in humans, we might just find out if reproductive cloning is in fact impossible or not.

California Bill Would Lift Ban on Paying Women for Eggs

nospam@example.com (Rebecca Taylor) — Tue, 14 May 2013 16:40:06 -0700

A new bill introduced into the California legislature would lift the ban on paying women for their eggs

AB 926, the Reproductive Health and Research Bill, says that to encourage reproductive health and research in the state, women need to be compensated for donating their eggs, a hot commodity in the embryonic stem cell research and infertility arenas....

So why would California want more women to go through such a process just for research purposes? AB 926 gives a list of research that would benefit from having more human eggs, which includes reducing the high volume of multiple pregnancies in IVF. But there is some very disturbing verbiage in AB 926 including the assertion that research will benefit from the intentional creation of excess embryos.

Continue reading at LifeNews >>

Is Sex-Selective IVF Harmless?

nospam@example.com (Rebecca Taylor) — Wed, 08 May 2013 12:46:51 -0700

Aussie boy: "Hey Ma, where are we going on vacation this year?"

Aussie mom: "We are doing something very special. We are going to circumvent the laws of our country and we are going to travel all the way to Thailand, stay in a fancy hotel for a week, and buy you a little sister!"

Aussie boy: "Good onya, Ma!"

If you are an Aussie couple dying to have a girl or boy, forget about the ban on sex-selective IVF and let Global Health Travel of Australia set it all up for you! Airfare, luxury accommodations and the child of your choice.

No joke.

Continue reading at Creative Minority Report >>

BioTalk, Episode 4: Biotechnology and the Church

nospam@example.com (Rebecca Taylor) — Mon, 06 May 2013 10:34:16 -0700

A very interesting discussion with Chelsea on the Church and biotechnology and how the Church is far more "forward" than the rest of society where we conclude that "It is not time for the Church to catch up to us. It is time for us to catch up with the Church."

Transhumanism Makes it Off, Off Broadway

nospam@example.com (Rebecca Taylor) — Fri, 03 May 2013 10:36:16 -0700

Themes of how we will relate to each other when we live in Ray Kurzweil's singularity and are no longer oragnic, just disembodied consciousnesses uploaded to the digital world, have made it to Broadway. Well off, off Broadway at least. Broadway World reports on "Love Machine":

What do a small town girl flirting with a satellite, a robot giving a lecture about transhumanism, and a man uploading his consciousness into the digital ether all have in common? Love. Love Machine is created to reflect the current trend of the way humans have come to rely on technology. Below, BroadwayWorld has a first look at the piece, debuting at Incubator Arts Project on May 10!

Continuing a long collaboration between theater and technology, the Love Machine team uses interactive, commercially available technologies, combined with improvisation and character-based writing techniques, to create a live experience blasting forward into the future and asking the questions of tomorrow.

In Part 1, the team explores the 1974 launch and abandonment of the space station Skylab through the loving eyes of Cindy, a lonely girl with no date to prom. Enter Skylab: a man-made satellite, strangely reminiscent of Fred Astaire. Together they embark on a musical journey through outer space.

Part 2 takes us to the year 2050 for a guest lecture on Transhumanism, a movement focused on furthering the human condition by means of science and technology. The talk is led by the robotically preserved consciousness of a transgender scientist and is followed by an audience Q & A.

Part 3 is a high tech interactive dance piece that asks the simple question: how does a disembodied consciousness find love?

That should be really interesting. I wonder how to theatrically portray a disembodied consciousness and whether the audience will have any idea of what they are viewing.

No matter. Transhumanist ideas are here to stay. Next it will be a blockbuster musical-comedy about wayward artificial limbs and dreams of becoming re-embodied. I can see the headline: "Transhumans Take Broadway By Storm!"

Have you talked with your kids about enhancements yet?

Toddler Gets Windpipe Grown From Her Own Stem Cells

nospam@example.com (Rebecca Taylor) — Wed, 01 May 2013 13:15:45 -0700

An adorable two year-old has a new lease on life thanks to pioneering doctors, a charitable Catholic hospital and her own stem cells. Little Hannah Warren was born without a trachea, the passageway that leads to the lungs. Although a tube was inserted from her esophagus to her lungs to help her breath, doctors told her parents that she would likely die.

Hannah is now recovering from a trachea transplant. The trachea was made from a plastic scaffold and stem cells taken from her bone marrow.

Continue reading at LifeNews >>

Little Everyday Good Things

nospam@example.com (Rebecca Taylor) — Tue, 30 Apr 2013 14:54:02 -0700

From the theoretical horrors of "In vitro eugenics," to the real horrors of Kermit Gosnell's abortuary and the bombings at the Boston Marathon, I am feeling a bit overwhelmed by the evil in the world. To fight this despair, I have been bringing to mind all of the good things that are in my life. This morning I saw this on Facebook from the Generation Life page:

Being wary of quote attributions on Facebook, I looked into these words of the Holy Father and found that the phrase (from Romans 12:21) was conveyed through a telegram from Cardinal Tarcisio Bertone, on behalf of Pope Francis, to Cardinal Sean OMalley, Archbishop of Boston, to give encouragement to the people of Boston.

Ruminating on this wisdom, I wondered how to combat great evil. Maybe with the crushing weight of all of the good. I suddenly felt compelled to write down that mental list I had been compiling of the all the good around me. The big stuff is easy: my marriage, my children, my faith, my extensive support group of homeschooling Catholic moms, the perspicacious commentary of the Archbold brothers.

But, I wanted to go a bit further and look for the little good things, ones that are everyday gifts that I often take for granted. Here is a list, in no particular order and certainly not exhaustive, of the little, everyday, good things in life that I am so very thankful for:

1. warm hug from a toddler in fuzzy footy pajamas

Continue reading at Creative Minority Report >>

Study Finds Adoption Hope for Happiness After IVF

nospam@example.com (Rebecca Taylor) — Mon, 29 Apr 2013 09:14:52 -0700

A study done by Swedish researchers has shown that couples that choose to adopt after failed IVF reported being happier than even couples who conceived naturally. From the Telegraph:

But a new study has found that, for those who go on to adopt, the earlier heartbreak can ultimately make for a happier family.

A study in Sweden found that couples who had adopted children after the disappointment of failing to conceive through fertility treatment appeared happier not only than other adoptive parents but even those who had children through natural means.

Of course this finding goes against the profit-seeking strategy of the IVF clinics that will keep taking a desperate couple's money for multiple failed attempts to get pregnant. I doubt the clinics will tell couples that they could really happy if they would adopt. But the researchers think this knowledge should be conveyed at a much earlier stage. Co-author Professor Marie Berg:

"The results show that it can be important to consider adoption as soon as couples seek medical help for infertility, especially now that we know that adoption enhances quality of life.

"As things stand, the issue of adoption is pursued only once IVF treatment has failed."

And some people are taking notice:

The researchers said it suggested that childless couples should be urged to consider adoption at a much earlier stage. It is a finding which boost the education secretary Michael Gove's drive to increase adoption rates in the UK.

There is one giant elephant in the room though. How can adoption rates increase if we keep aborting millions of children every year? We don't often think of abortion as a driving force for couples to seek IVF, but with "unwanted" babies being aborted instead of given a chance at life with a loving couple, the heartbreak of being childless drive many to straight to the IVF clinic.

This study maybe an important finding for both women with "unwanted" pregnancies and infertile couples a like. Adoption does bring happiness.

Brain Cells Direct From Bone Marrow Stem Cells

nospam@example.com (Rebecca Taylor) — Tue, 23 Apr 2013 14:43:38 -0700

Sometimes in science the best discoveries are those that are unexpected. Researchers in California were trying to get bone marrow stem cells to grow by introducing an antibodies to the cells. Instead the cells began to form neural cells. U.S. News & World Report has the story:

Scientists have discovered an antibody that can turn stem cells from a patient's bone marrow directly into brain cells, a potential breakthrough in the treatment of neurological diseases and injuries.

Richard Lerner, of the Scripps Research Institute in California, says that when a specific antibody is injected into stem cells from bone marrowwhich normally turn into white blood cellsthe cells can be triggered to turn into brain cells.

"There's been a lot of research activity where people would like to repair brain and spinal cord injuries," Lerner says. "With this method, you can go to a person's own stem cells and turn them into brain cells that can repair nerve injuries."

Neural cells straight from your own bone marrow. Remarkable.

Continue reading at LifeNews >>

The Church Is Not Backward, But Forward

nospam@example.com (Rebecca Taylor) — Mon, 22 Apr 2013 09:20:20 -0700

It is as inevitable as the passing of time. Once there is a new pope, the world begins to wonder when the Catholic Church is going to leave its "medieval thinking" behind and join the "modern" age. It is the 21st century after all, and the Church needs to stop being so "backward."

I am a cradle Catholic, and, when I was young, I subconsciously believed that the Church was "behind the times" and "out of touch."

As I began my career and worked in cutting-edge biotech laboratories, there was always a nagging question: How can my Church, so rooted in the past, have something relevant to say about modern technologies like stem-cell research, cloning and genetic engineering that are coming in the future?

Then I began researching these technologies and discovered something that changed the way I viewed my Church and my faith. Elbow deep in the latest biotechnology news, I discovered that the Church was far from backward, out of touch and irrelevant.

It is the most forward-thinking institution I have ever encountered and more relevant today than ever.

Continue reading at National Catholic Register >>

Reactions to Uterus Transplant Pregnancy

nospam@example.com (Rebecca Taylor) — Wed, 17 Apr 2013 10:05:54 -0700

Part of being a blogger is learning that people, even ones on your side, will misread, misunderstand, and misrepresent what you are saying. Being human, many of us only read headlines, or skim through a piece missing the major points, or infer things that simply are not implied. Knowing this, I try not to let reactions to my posts get under my skin.

For some reason the reactions to yesterday's news about the pregnancy of the woman who underwent a uterus transplant really affected me. To recap, a woman born without a uterus was transplanted with a uterus from a deceased woman. She then underwent IVF and is now confirmed to be pregnant.

Many of the comments I have read state that the only thing wrong with this is the IVF. If she had gotten pregnant naturally this would be fine. I also read a lot of comments that compare a uterus transplant to a kidney or heart transplant. The thought is that if those are morally acceptable then this should be to.

I guess I am disheartened that many of the comments echo the sentiments of the rest of society: the emotional appeals to what the parents want with little thought to how a procedure affects the health and well-being of the child.

Let us think about this critically instead of emotionally.

A uterus transplant is not a necessary procedure. This woman was not going to die if she did not receive a womb. This is nothing like a kidney or heart transplant. The point was so that she could be pregnant evidenced by the fact that the uterus will be removed after the child is delivered.

Since the uterus came from a deceased woman, presumably no other lives were put at risk to retrieve the organ. This is not the case with a live uterus donor which is also being attempted. To put the health and safety of the otherwise healthy woman donating the uterus at risk to provide a organ that is not essential for life is not ethical.

Beyond the actual transplant, let us consider the child that is now being gestated in this transplanted uterus. This child was purposefully placed in a womb that is a potentially dangerous place. The mother has to take immunosuppressant drugs so she will not reject the uterus. As experts said there is significant risk of birth defects and pre-term labor here. The child was created in a lab and intentionally put at risk in an experimental womb just so that this woman could experience pregnancy.

Remember there is a PERSON in that womb whose life hangs in the balance. He or she could suffer life-long consequences. Is this treating him or her with the utmost respect deserving of every person?

Sure it would be nice if every woman with a deformed or malfunction uterus could get a replacement, but how many children do we need to put at risk to perfect this procedure? In other high-risk medical procedures like heart or kidney transplants, the possible reward outweighs the risk because the patient is already in a life-threatening situation. But with a uterus transplant there is no life-threatening illness to treat. Is it ethical to intentionally put the life of a child at risk for a non-life threatening problem?

There are a lot of medical advancements that we could have if we treated research subjects unethically. Let us not forget that the child is also a subject in this experiment. Are we treating him or her ethically or as a regrettable, but acceptable, causality if this fails?

I fear that the attitude toward this child is the same as all the children of artificial reproductive technologies (ART) that came before. The priority is what the parents want. The health and safety of the child is secondary. A recent review of ART in the Journal of Reproductive BioMedicine Online, written by scientists in the field, reiterates that idea that in the fertility industry, many have a "let's see if it works and ask questions about safety later" attitude. Is that what is happening here?

I think if we continue on with this perspective where the health and safety of the next generation is not the first priority, things like "in vitro eugenics" are sure to follow. Dr. Sparrow is right that concerns about safety are unlikely to stop the creation of generations of embryos in the lab because, so far, concerns about the children hasn't stopped any ART. It is up to us to be the voice of the voiceless.

I realize that the Catholic Church has not officially come out against uterus transplants, but that does not mean we cannot think critically about it and come to the conclusion that this is unethical. I often ask myself these questions when evaluating advances in biotechnology. I think it applies here:

Does this technology disrespect or unnecessarily endanger human life at any point from the very beginning to natural death? Does it reduce human life to a biological commodity? Does it require that a human organism be used or destroyed?

I have come to the conclusion that the uterus transplant does intentionally endanger the life of an innocent child simply so a woman can be pregnant. I know others disagree. I just want to make sure that the discussions surrounding this procedure are grounded in the MOST important consideration, the health and well-being of the child, and not in the emotional appeal to what adults desire.

Woman With Uterus Transplant Confirmed Pregnant

nospam@example.com (Rebecca Taylor) — Tue, 16 Apr 2013 09:28:23 -0700

Doctors have announced that the woman that received a womb transplant is now pregnant. From RedOrbit:

The Turkish woman who, two years ago, became the first person in the world to have a successful womb transplant from a deceased donor is pregnant, various media outlets are reporting.

Twenty-two-year-old Derya Sert, who was born without a womb, had been receiving in vitro fertilization (IVF) treatments since the successful transplant, which took place in August 2011 at Akdeniz University Hospital in Turkeys southern province of Antalya, the AFP news agency reported on Friday.

According to Reuters, the hospital released a statement stating early test results were consistent with pregnancy and that Sert was in good health.

Now it is time to pray for that child. Pray that he or she is born healthy with no complications. We need to pray because even the doctors admit that things may go wrong:

Experts however warn the pregnancy carries several health risks to the patient as well as to the baby, including birth defects due to the use of immunosuppressive drugs as well as preterm delivery.

I think herein lies the problem. This child is the experiment, not part of an experiment, but is the actual experiment. Why else would you transplant a uterus to a woman who was born without one? It is not so she can menstruate for a few years. It is so she can gestate a baby. A baby that had his or her start in a laboratory not in a loving embrace.

The idea of a child as the experiment is not new. We have been experimenting with the next generation without their consent for a long time. We are still experimenting on them. The fact is we have no idea what the long-term physical and emotional effects of IVF, PGD, ICSI or other artificial reproductive technologies (ART) even are and yet we continue on. This uterus transplant is no different.

The avant-garde attitude toward the creation of children will continue on with the health and well-being of the children produced as an after-thought. Case in point, Dr. Robert Sparrow's paper "In vitro eugenics" in the Journal of Medical Ethics where he explores possibility of creating embryos in the lab, then using the stem cells from those embryos to create egg and sperm cells, and then using those gametes to create more embryos. Essentially, this would take human reproduction into the laboratory not just for one generation, but for generation after generation. These embryos would be "orphaned at conception." Unfortunately, this technology of producing egg and sperm from stem cells is no longer science fiction. Scientists have already accomplished this in mice and are discussing and developing strategies to doing the same in humans.

Sparrow points out that safety concerns for the children produced with "in vitro eugenics" will likely not prevent the practice because frankly we have had little concern for safety in any previous ART technique. Sparrow writes:

However, there are a number of reasons to believe that concerns about safety and risk are unlikely to prove an insurmountable barrier to the ethical creation of designer babies by in vitro eugenics. To begin with, as I noted above, these concerns arise regarding every new reproductive technology involving the manipulation of embryos. Until a generation of children produced by IVF (or intracytoplasmic sperm injection or cytoplasmic transfer) have lived out their natural lifespan, we will not know whether IVF (or any of these other technologies) is safeand we certainly did not know this at the time at which those technologies were first trialled. Thus, in vitro eugenics would not raise any issues we have not confronted before.

I think we can add uterus transplant from a deceased donor to his list of techniques where we did not know the whether the technique was "safe" before we tried it.

Let me provide an alternative way to view children. A view where children are to be treated with the utmost respect, not just from birth, but from conception. A view of children as the beautiful fruit of the love between a husband and wife not as the product of technological intervention. Let me quote Donum Vitae:

The child is not an object to which one has a right, nor can he be considered as an object of ownership: rather, a child is a gift, the supreme gift and the most gratuitous gift of marriage, and is a living testimony of the mutual giving of his parents.

And then Charter for Health Care Workers:

"The desire for a child, sincere and intense though it be, by the spouses, does not legitimize recourse to techniques which are contrary to the truth of human procreation and to the dignity of the new human being. The desire for a child gives no right to have a child. The latter is a person, with the dignity of a 'subject.' As such, it cannot be desired as an 'object.' The fact is that the child is a subject of rights: the child has the right to be conceived only with full respect for its personhood."

I think it time we listen to the wisdom of the Catholic Church on procreation. Otherwise "in vitro eugenics" may only be the first in the long line of unethical techniques that treat children as objects and not as the gifts that they truly are.

Vatican Holds Second Adult Stem Cell Research Conference

nospam@example.com (Rebecca Taylor) — Fri, 12 Apr 2013 10:51:13 -0700

This week the Vatican is hosting another adult stem cell conference bringing together some of the top scientists in the field. The conference, the second held by the Vatican, is called "Regenerative Medicine A Fundamental Shift in Science & Culture." It is a collaboration between the Pontifical Council for Culture, NeoStem, an adult stem cell company, STOQ International, a non-profit that encourages dialogue between Church and culture, and The Stem for Life Foundation, a non-profit dedicated to spreading the good news about adult stem cells.

According to Dr. Robin Smith, CEO of NeoStem and President of the Stem For Life Foundation, the conference will focus on the all of the misconceptions surrounding stem cell science. From the conference press release:

"We created this event so that we could educate the world on the ability of adult stem cell therapies to address countless diseases and medical conditions, reducing suffering on a truly global scale," said Dr. Robin Smith, President of The Stem for Life Foundation and CEO of NeoStem. "To tell this story of hope and healing, and to address the many misconceptions surrounding stem cell therapies, we have gathered leaders and pioneers of the regenerative medicine industry, as well as patients who have received adult stem cell therapies, journalists, ethicists, educators, policy experts and religious officials. The human body holds the secrets to healing and this landmark event will sound a clarion call."

Continue reading at Life News >>

"In vitro eugenics" straight from Huxley's Brave New World

nospam@example.com (Rebecca Taylor) — Wed, 10 Apr 2013 12:30:45 -0700

I read somewhere that while both George Orwell's 1984 and Aldous Huxley's Brave New World contained dystopian futures, Huxley's world, where humans are made in "hatcheries" and the people were kept compliant, not by the threat of Big Brother, but by the numbing of their senses with the pleasure-inducing drug "soma," was a more plausible scenario.

After reading "In vitro eugenics" by Dr. Robert Sparrow in the Journal of Medical Ethics, I have to agree. Dr. Sparrow explores the possibility of creating embryos in the lab, then using the stem cells from those embryos to create egg and sperm cells, and then using those gametes to create more embryos. Essentially, this would take human reproduction into the laboratory not just for one generation, but for generation after generation. These embryos would be "orphaned at conception." They "would have no genetic parents: there would be no living individualor indeed individual that had ever livedwho could be described as the genetic progenitor of such embryos." Sparrow calls this "in vitro eugenics."

Continue reading at Creative Minority Report >>